Bioactive Profiling of the Essential Oil from the Leaves of Abrus Precatorious in Rajasthan India

Alagbe Olujimi  John; Shittu Daniel Muritala; Ojediran Taiwo K; Anaso Emmanuel U; Daniel Nnadozie Anorue

doi:10.59890/ijatss.v3i7.72

Authors

Alagbe Olujimi John Adjunct Lecturer, Gandhi College of Agriculture, Rajasthan, India
Shittu Daniel Muritala Ladoke Akintola University of Technology, Oyo State, Nigeria
Ojediran Taiwo K Ladoke Akintola University of Technology, Oyo State, Nigeria
Anaso Emmanuel U University of Abuja, Nigeria
Daniel Nnadozie Anorue University of Abuja, Nigeria

DOI:

https://doi.org/10.59890/ijatss.v3i7.72

Keywords:

Abrus Precatorious, Antibiotics, Essential Oil, Compounds, Food Safety, Sustainability, Resistance

Abstract

Medicinal plants have a long tradition as therapeutic agents and have also been part of human and animal diet. They contain numerous bioactive components that are generally considered to be a safe replacement for antibiotics. They also create a pollution free environment and has no withdrawal period. The results of the gas chromatography mass spectrometry of Abrus precatorious oil revealed the presence of 19 bioactive compounds. These compounds include, γ-terpinene, β-caryophyellene, methylparaben, 3- pyridinol, dibutyl phthalate, α-terpineol, D-allose, limonene, α-pinene, p-cymene, n-hexadecanoic acid, 1-hexadecyne, octadecanoic acid ethyl ester, 2-methoxy-4-vinaylphenol, di-hydroxypropyl ester, 9,17-octadecadienal, oleic acid and 2-heptadecanone. D-allose (31.06 %), n-hexadecanoic acid (14.50 %), p-cymene (10.06 %), γ-terpinene (7.93 %), 3- pyridinol (5.90 %), β-caryophyellene (5.14 %), α-pinene (4.95 %), limonene (4.80 %) and α-terpineol (4.08 %) were the most abundant compounds. However, all phyto-components have numerous therapeutic applications (anti-inflammatory, cytotoxic, antioxidant, anti-helminthic, anti-diuretic, anti-cancer, antiviral, antimicrobial, antifungal, hepato-protective, gastro-protective, immuno-modulator, antidiarrheal, amongst others) and can be used in the treatment of diseases or infections

References

Abdulkabir Oladele Oladimeji, Oluwatoyin Babatunde, Rukayat Titilayo Musa, Fausat Adeola M’civer, Abdulazeez Tunbosun Lawal, Isiaka Ajani Ogunwande (2016). GC-MS analysis and cytotoxic activity of essential oils from the leaves of Abrus precatorius L. Gaertn. Asian Pacific Journal of Tropical Disease, 6(5): 372-375

Adewale, A.O., Alagbe, J.O., Adeoye, Adekemi. O. (2021). Dietary Supplementation of Rauvolfia Vomitoria Root Extract as A Phytogenic Feed Additive in Growing Rabbit Diets: Haematology and serum biochemical indices. International Journal of Orange Technologies, 3(3): 1-12.

Alagbe Olujimi John (2024). Novel phytogenics’ impact on weaned pigs growth performance, haematology and serum biochemical indicators. Black Sea Journal of Agriculture, 7(2): 82-89.

Alagbe, J.O (2022). Use of medicinal plants as a panacea to poultry production and food security: A review. Gospodarka I Innowacje 22(2022): 1-12.

Alagbe, J.O., Shittu, M.D and Tanimomo, Babatunde K. (2022). Influence of Anogeissusleio carpus stem bark on the fatty acid composition in meat of broiler chickens. European Journal of Life Safety and Stability 14(22): 13-22.

AOAC, 1997. Official Methods of Analysis, 16th ed. Association of Official Analysis Chemists International. AOAC International, Washington DC.

Choi, J., Park, N., Hwang, S., Sohn, J., Kwak, I., Cho, K.K and Choi, I. (2013). The antibacterial activity of various saturated and unsaturated fatty acids against several oral pathogens. Journal of Environmental Biology, 34, 673- 676

Daniel Nnadozie Anorue, Friday Ubong and Alagbe Olujimi John (2023). Investigating the effects of pawpaw (Carica papaya) essential oil dietary supplementation on the growth performance and carcass characteristics of broilers. Research in: Agricultural and Veterinary Sciences, 7(3): 164 - 174.

Doughari, J.H. (2012). Phytochemicals: Extraction Methods, Basic Structures and Mode of Action as Potential Chemmotherapeutic Agents- A Global Perspective of Their Role in Nutrition and Health. Dr. Venketeshwer Rao. Ed). ISBN: 978- 953-51-0296-0. Intech.

Gawali, P and Jadhav, B.L. (2011). Antioxidant activity and antioxidant phytochemical analysis of mangrove species Sonneratia albaand Bruguiera cylindrical. Asian Journal of Microbiology, Biotechnology & Environmental Sciences, 13 (2), 257-261.

Gnanavel, V and Mary Saral, A. (2013). “GC-MS analysis of petroleum ether and ethanol leaf extracts from abrus precatorius linn,” International Journal of Pharmaceutical and Biological Science, 4(3): 21-24

Greay SJ, Hammer KA. (2015). Recent developments in the bioactivity of mono- and diterpenes: anticancer and antimicrobial activity. Phytochem Rev 2015; 14(1): 1-6.

Gul MZ, Ahmad F, Kondapi AK, Qureshi IA, Ghazi IA. (2013). Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts--an in vitro study. BMC Complement Alternative Medicine, 2013; 13: 53.

Huang M, Sanchez-Moreiras AM, Abel C, Sohrabi R, Lee S, Gershenzon J, et al. (2012). The major volatile organic compound emitted from Arabidopsis thaliana flowers, the sesquiterpene (E)-β-caryophyllene, is a defense against a bacterial pathogen. New Phytol 2012; 193(4): 997-1008

James, H.D and Mom Saa-Aondo (2021). Phytochemical analysis of crude methanol extracts and antimicrobial activity of n-hexane fractions of methanol seed and pod extracts of Prosopis africana on some selected microoganisms. Pharmacology Online, 2: 121-137.

Jang DH, Hoffman RS, Nelson LS. (2010). Attempted suicide, by mail order: Abrus precatorius. J Med Toxicol 2010; 6(4): 427-30.

John, A.O. (2024a). Impact of dietary supplementation of Rhamnus prinoides leaf extract on the growth performance, nutrient retention and intestinal microbial count of Japanese quails. Brazilian Journal of Science, 3(5): 40-50.

John, A.O. (2024b). Clerodendron splendens leaf extract supplementation in weaner rabbits: impact on growth performance, haematology and intestinal microbial population. Cerrado: Agricultural and Biological Research, 1(1): 21-31.

John, A.O. (2024c). Effect of coconut shell extract on the growth performance and some haemato-biochemical parameters of broiler chicken. Brazilian Journal of Science, 3(6): 82-95.

John, A.O. (2024d). Effect of performance, serum biochemistry and heamatological components of feeding Japanese quails phytogenic feed additions comprising Megaphrynium macrostachyum leaves. Brazilian Journal of Science, 3(5): 51-64.

John, A.O. (2024e). Growth performance, haemato-biochemical indices of broiler chicken fed Aristochia indica as a phytogenic feed additive. Cerrado: Agricultural and Biological Research, 1(1): 42-53.

Kim NC, Kim DS, Kinghorn AD. (2022). New triterpenoids from the leaves of Abrus precatorius. Nat Prod Letters, 16(4): 261-6.

Klavina, L., Springe, G., Nikolajeva, V., Martsinkevich, I., Nakurte, I, et al., (2015). Chemical composition analysis, antimicrobial activity and cytotoxicity screening of moss extracts (moss phytochemistry). Molecule, 20, 17221-17243.

Musa, B., Alagbe, J.O., Adegbite Motunrade Betty, Omokore, E.A. (2020). Growth performance, caeca microbial population and immune response of broiler chicks fed aqueous extract of Balanites aegyptiaca and Alchornea cordifolia stem bark mixture. United Journal for Research and Technology, 2(2):13-21.

Namkeleja, H.S., Tarimo, N.T.C. & Ndakidemi, P.A. (2014). Allelopathic Effects of Argemone Mexicana to Growth of Native Plant Species. American Journal of Plant Sciences, 5 (9), 1336- 1344

Nurdiani, R., Firdaus, M and Prihanto, A.A. (2012). Phytochemical and pharmacological studies of ethanolic extract from the leaf of mangrove plant (Rhyzophoramucronata) from Porong River Estuary. Journal of Basic Science and Technology, 1 (2), 27-29

Odozi, B.E., Ibeh I N., Odozi P.I., Osakwe, A.A & Otoikhian, C.S.O. (2014). Antimicrobial activity of aqueous and methanol extract of Prosopis africana on selected bacteria isolates. IndoAmerican Journal of Life Science and Biotechnology, 2 (2), 10-14.

Olajuyige, O.O., Babalola, A.E. & Afolalayan, A.J. (2011). Antibacterial and phytochemical screening of crude ethanolic extracts of Waltheria Linn. African Journal of Microbiology Research, 5 (22), 3760-3764.

Omokore, E.O and Alagbe, J.O. (2019). Efficacy of dried Phyllantus amarus leaf meal as an herbal feed additive on the growth performance, haematology and serum biochemistry of growing rabbits. International Journal of Academic Research and Development. 4(3): 97-104.

Prabhu, V.V and Guruvayoorappan C. (2012). Phytochemical screening of methanolic extract of mangrove Avicennia marina (Forssk.) Vierh Der Pharmacia Sinica, 3 (1), 64-70

Russo A, Formisano C, Rigano D, Senatore F, Delfine S, Cardile V, et al. (2013). Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions. Food Chem Toxicol 2013; 55: 42-7

Shanmugapriya, R., Ramanathan, T and Renugadevi, G. (2012). Phytochemical Characterization and Antimicrobial Efficiency of Mangrove Plants Avicennia marina and Avicennia officinalis. International journal of Pharmaceutical & Biological Archives, 3 (2), 348-351.

Shittu, M.D., Alagbe, J.O., Alaba, O., Okanlawon, E.O., Adelakun, F.A., Emmanuel, E.O and Adejumo, D.O. (2024). Effect of ginger, garlic and Negro pepper on the gut microbes, gut histomorphometry and pathological assessment of selected organs of broiler chickens. Association of Deans of Agriculture in Nigerian Universities, 5: 105-121.

Shivam V. (2022). Phytochemical analysis of Abrus precatorius and leaf extract and its application. International Journal of Creative Research Thoughts, 10(11): d529-d538.

Simlai, A. & Roy A. (2012). Analysis of and correlation between phytochemical and antimicrobial constituents of Ceriops decandra, a medicinal mangrove plant, from Indian Sundarban estuary. Journal of Medicinal Plants Research, 6 (32), 4755-4765

Singh Sharma., Alagbe Olujimi John., Liu Xing., Sharma Ram and Kumar Amita (2022). Comparative analysis of ethanolic Juniperus thurifera leaf, stem bark and root extract using gas chromatography and mass spectroemetry. International Journal of Agriculture and Animal Production, 2(6): 18-27.

Solanki, A and Zaveri, M. (2012). “Pharmacognosy, phytochemistry and pharmacology of Abrus precatorius leaf: A review,” Int. Journal of Pharmaceutical Science and Research, 13(2): 71–76.

Xiao ZH, Wang FZ, Sun AJ, Li CR, Huang CG, Zhang S. (2011). A new triterpenoid saponin from Abrus precatorius Linn. Molecules 2011; 17(1): 295-302